Delayed recognition of fatal invasive meningococcal disease in adults

Delayed recognition of fatal invasive meningococcal disease in adults

INTRODUCTION Invasive meningococcal disease can be difficult to detect early in its course when patients may appear well and the severity of their illness is obscured by non-specific complaints. CASE PRESENTATION We report five cases of meningococcal sepsis in adult patients who presented to an emergency department early in the course of their disease, but whose severity of illness was not re...

Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands

Invasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully implemented a single dose of meningococcal serogroup C conjugate vaccine at the age of 14 months a...

Invasive meningococcal disease in childhood.

Surveillance of Invasive Meningococcal Disease

Invasive meningococcal disease (IMD) is a nationally reportable disease in Canada. Since 1985, the Laboratory Centre for Disease Control (LCDC) has enhanced IMD surveillance to correlate case-by-case information provided by the provinces and territories with detailed laboratory studies done at the National Laboratory for Bacteriology at LCDC. This report provides information on IMD from 1 Janua...

Underestimation of Invasive Meningococcal Disease in Italy.

Knowing the incidence of invasive meningococcal disease (IMD) is essential for planning appropriate vaccination policies. However, IMD may be underestimated because of misdiagnosis or insufficiently sensitive laboratory methods. Using a national molecular surveillance register, we assessed the number of cases misdiagnosed and diagnoses obtained postmortem with real-time PCR (rPCR), and we compa...